EFSA toxicology reference values
4-Methylpent-3-en-2-one
SOURCE
efsa openfoodtox 3 0 export repository
4-Methylpent-3-en-2-one (CAS 141-79-7). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.
4-Methylpent-3-en-2-one is a cannabis analyte contaminant represented in the cannabis public dataset.
CAS 141-79-7
Cannabis Analyte
Substance Identity
Analyte identity and classification used for this cannabis substance page.
SOURCE
efsa substances
Analyte name
4-Methylpent-3-en-2-one
CAS number
141-79-7
Contaminant class
Cannabis Analyte
Contaminant Class Badge
Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.
SOURCE
State Cannabis Regulations
Cannabis Analyte
Cannabis contaminant class used to group state testing rows.
Dataset Snapshot
Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.
SOURCE
cannabis page data
Quality score
2
thin
Jurisdictions
0
No state rows
Lab/analyte rows
0
0 failed (-)
Potency samples
0
141-79-7
EFSA Substance Identity
EFSA substance identity rows matched by chemical name or CAS.
SOURCE
efsa openfoodtox 3 0 export repository
4-Methylpent-3-en-2-one
CAS 141-79-7 / mono-constituent substance
C6H10O / 4 dossier(s)
EFSA Reference Values
Reference values from efsa_reference_values_v2 for toxicology and food-safety context.
SOURCE
efsa openfoodtox 3 0 export repository
| Descriptor | Value | Population | Endpoint | Body |
|---|---|---|---|---|
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | other: |
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | - |
| margin of safety | - | consumers | - | - |
EFSA Study Results
Endpoint-level study rows from efsa_study_results matched to this substance.
SOURCE
efsa openfoodtox 3 0 export repository
| Endpoint | Species | Route | Effect | Assessment |
|---|---|---|---|---|
| boiling point | - | - | - | experimental study |
| appearance / physical state / colour | - | - | - | experimental study |
| solubility in organic solvents / fat solubility | - | - | - | experimental study |
| melting point/freezing point | - | - | - | Not reported |
| refractive index | - | - | - | refractive index: (1.442 - 1.447) dimensionless |
| other: | - | - | - | relative density: (0.862 - 0.868) dimensionless |
| water solubility | - | - | - | experimental study |
| Carcinogenicity_EU_PPP | - | - | - | The Panel on Food Additives and Flavourings (FAF Panel) of the European Food Safety Authority was requested to evaluate the genotoxic potential of the flavouring substances from subgroup 1.2.1 of FGE.19 in the Flavouring Group Evaluation 204 (FGE.204). |
| Carcinogenicity_EU_PPP | - | - | - | The European Commission requests EFSA to carry out a safety assessment on the substances oct-1-en-3-ol, pent-1-en-3-ol, hex-1-en-3-ol, dec-1-en-3-ol, 1-hepten-3-ol, oct-1-en-3-one, pent-1-en-3-one, oct-1-en-3-yl acetate and oct-1-en-3-yl butyrate [FL-no: 02.023, 02.099, 02.104, 02.136, 02.155, 07.081, 07.102, 09.281 and 09.282], evaluated in FGE.205 Revision 1, in accordance with Commission Regulation (EC) No 1565/2000. |
| Carcinogenicity_EU_PPP | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. The present Flavouring Group Evaluation 204 (FGE.204), corresponding to subgroup 1.2.1 of FGE.19, concerns 16 mono-unsaturated, aliphatic, alpha,beta-unsaturated ketones and two precursors for such ketones. The alpha,beta-unsaturated aldehyde and ketone structures are structural alerts for genotoxicity and the data on genotoxicity previously available did not rule out the concern for genotoxicity for these 18 flavouring substances. |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific opinion to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. In Flavouring Group Evaluation 63, Revision 1 (FGE.63Rev1) the EFSA considered 19 flavouring substances from two groups of flavouring substances consisting of aliphatic secondary alcohols, ketones and related esters evaluated by the JECFA at its 59th meeting and at its 69th meeting. The present revision of FGE.63, FGE.63Rev2, includes the consideration of one additional substance, 4-methylpent-3-en-2-one [FL-no: 07.101]. This substance [FL-no: 07.101] was evaluated by the JECFA at its 59th meeting and the substance is an alpha,beta-unsaturated ketone originally allocated to and evaluated in FGE.204 in which it was considered not to be of concern with respect to genotoxicity. Therefore, the present revision of FGE.63, FGE.63Rev2, considers 20 flavouring substances evaluated by the JECFA. The Panel concluded that the 20 substances in the JECFA flavouring group of aliphatic secondary alcohols, ketones and related esters are structurally related to the group of 49 saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids evaluated in FGE.07Rev4. |
| Genetic Toxicity | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. The present Flavouring Group Evaluation 204 (FGE.204), corresponding to subgroup 1.2.1 of FGE.19, concerns 16 mono-unsaturated, aliphatic, alpha,beta-unsaturated ketones and two precursors for such ketones. The alpha,beta-unsaturated aldehyde and ketone structures are structural alerts for genotoxicity and the data on genotoxicity previously available did not rule out the concern for genotoxicity for these 18 flavouring substances. |
Cross-Reference to Chemicals / Cosmetics / Food
Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.
SOURCE
core public cross-reference
Frequently Asked Questions
FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.
SOURCE
page FAQ dataset
What is the regulatory limit for 4-Methylpent-3-en-2-one in cannabis?
4-Methylpent-3-en-2-one does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.
Which states test for 4-Methylpent-3-en-2-one?
4-Methylpent-3-en-2-one does not have state-level cannabis testing rows in the fetched page data.
What are the EFSA reference values for 4-Methylpent-3-en-2-one?
4-Methylpent-3-en-2-one has 4 EFSA OpenFoodTox reference value rows in the cannabis database, including TTC Cramer Class II, margin of safety.
Is 4-Methylpent-3-en-2-one also regulated in cosmetics or food?
4-Methylpent-3-en-2-one has a cosmetics ingredient cross-reference with EU status permitted. EFSA food/toxicology context is available on this page.