EFSA toxicology reference values

Methyl 2-octynoate

SOURCE EFSA

Methyl 2-octynoate (CAS 111-12-6). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.

Methyl 2-octynoate is a cannabis analyte contaminant represented in the cannabis public dataset.

CAS 111-12-6 Cannabis Analyte

Substance Identity

Analyte identity and classification used for this cannabis substance page.

SOURCE EFSA
Analyte name
Methyl 2-octynoate
CAS number
111-12-6
Contaminant class
Cannabis Analyte

Contaminant Class Badge

Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.

SOURCE State Cannabis Regulations
Cannabis Analyte Cannabis contaminant class used to group state testing rows.

Dataset Snapshot

Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.

SOURCE cannabis page data
Quality score
2
thin
Jurisdictions
0
No state rows
Lab/analyte rows
0
0 failed (-)
Potency samples
0
111-12-6

EFSA Substance Identity

EFSA substance identity rows matched by chemical name or CAS.

SOURCE EFSA
Methyl 2-octynoate
CAS 111-12-6 / mono-constituent substance
c9h14o2 / 1 dossier(s)

EFSA Reference Values

Reference values from efsa_reference_values_v2 for toxicology and food-safety context.

SOURCE EFSA
DescriptorValuePopulationEndpointBody
TTC Cramer Class I 30 µg/kg bw/day consumers - -

EFSA Study Results

Endpoint-level study rows from efsa_study_results matched to this substance.

SOURCE EFSA
EndpointSpeciesRouteEffectAssessment
Carcinogenicity_EU_PPP - - - The Scientific Panel on Food Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217 EC and its consecutive amendments. The JECFA has evaluated 37 flavouring substances in the group aliphatic, linear alpha,betaunsaturated aldehydes, acids and related alcohols, acetals and esters at their 63rd meeting. Five of the 37 flavouring substances evaluated by the JECFA are not in the Register [(E)-2-octen-1-ol (JECFA-no: 1370), (E)-2-butenoic acid (JECFA-no: 1371), trans-2-hexenyl pentanoate (JECFA-no: 1379), (E)-2-nonenoic acid (JECFA-no: 1380), mixture of (Z)-3-hexenyl propionate and (E)-2-hexenyl propionate (JECFA-no: 1382)]. Twenty-three substances are alpha,beta-unsaturated aldehydes and ketones considered with respect to genotoxicity in subgroup 1.1.1 of FGE.19, for which a final conclusion as to its genotoxic properties could not be reached and additional data were requested. This consideration therefore only deals with nine alpha,beta-unsaturated acids or esters hereof. The Panel concluded that the nine substances in the JECFA flavouring group of aliphatic, linear alpha,beta-unsaturated carboxylic acids and related esters are structurally related to the group of branched- and straight-chain unsaturated carboxylic acids and esters of these and straight-chain aliphatic saturated alcohols evaluated by EFSA in the Flavouring Group Evaluation 05, Revision 2 (FGE.05Rev2).
Genetic Toxicity - - - The Scientific Panel on Food Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217 EC and its consecutive amendments. The JECFA has evaluated 37 flavouring substances in the group aliphatic, linear alpha,betaunsaturated aldehydes, acids and related alcohols, acetals and esters at their 63rd meeting. Five of the 37 flavouring substances evaluated by the JECFA are not in the Register [(E)-2-octen-1-ol (JECFA-no: 1370), (E)-2-butenoic acid (JECFA-no: 1371), trans-2-hexenyl pentanoate (JECFA-no: 1379), (E)-2-nonenoic acid (JECFA-no: 1380), mixture of (Z)-3-hexenyl propionate and (E)-2-hexenyl propionate (JECFA-no: 1382)]. Twenty-three substances are alpha,beta-unsaturated aldehydes and ketones considered with respect to genotoxicity in subgroup 1.1.1 of FGE.19, for which a final conclusion as to its genotoxic properties could not be reached and additional data were requested. This consideration therefore only deals with nine alpha,beta-unsaturated acids or esters hereof. The Panel concluded that the nine substances in the JECFA flavouring group of aliphatic, linear alpha,beta-unsaturated carboxylic acids and related esters are structurally related to the group of branched- and straight-chain unsaturated carboxylic acids and esters of these and straight-chain aliphatic saturated alcohols evaluated by EFSA in the Flavouring Group Evaluation 05, Revision 2 (FGE.05Rev2).

Frequently Asked Questions

FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.

SOURCE Regulatory source

What is the regulatory limit for Methyl 2-octynoate in cannabis?

Methyl 2-octynoate does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.

Which states test for Methyl 2-octynoate?

Methyl 2-octynoate does not have state-level cannabis testing rows in the fetched page data.

What are the EFSA reference values for Methyl 2-octynoate?

Methyl 2-octynoate has 1 EFSA OpenFoodTox reference value row in the cannabis database, including TTC Cramer Class I.

Is Methyl 2-octynoate also regulated in cosmetics or food?

Methyl 2-octynoate has a cosmetics ingredient cross-reference with EU status restricted. EFSA food/toxicology context is available on this page.