CIR Review Summary May 6, 2026 3 min read

Thiodipropionic Acid and Its Dialkyl Esters: CIR Safety Assessment Summary

CIR safety assessment summary for Thiodipropionic Acid and Its Dialkyl Esters: ingredients reviewed, panel verdict, use concentration context, conditions,.

Thiodipropionic Acid and Its Dialkyl Esters appears in a CIR safety assessment covering Thiodipropionic Acid and Its Dialkyl Esters. The panel verdict for the report is safe with restrictions. The CIR Expert Panel concludes that dilauryl thiodipropionate, thiodipropionic acid, dicetyl thiodipropionate, dimyristyl thiodipropionate, distearyl thiodipropionate, and ditridecyl thiodipropionate are safe as cosmetic ingredients in the practices of use and concentration given in this safety assessment when formulated to be nonirritating.

FieldCIR value
Primary ingredientThiodipropionic Acid and Its Dialkyl Esters
CIR verdictsafe with restrictions
Report typeSafety Assessment
Date1 In 2007
CAS numbers123-28-4, 111-17-1, 3287-12-5, 16545-54-3, 693-36-7, 10595-72-9
Conditions or carve-outs

Ingredients Reviewed

The review scope matters because CIR conclusions often apply to an ingredient family rather than a single INCI name. In this report, the ingredient list includes Thiodipropionic Acid and Its Dialkyl Esters.

Safety Conclusion

The conclusion for Thiodipropionic Acid and Its Dialkyl Esters should be read as a CIR panel conclusion, not a regulatory limit. CIR assessments summarize expert-panel safety determinations for cosmetic use, while legal status still depends on the jurisdiction and product category.

Conditions

The CIR Expert Panel concludes that dilauryl thiodipropionate, thiodipropionic acid, dicetyl thiodipropionate, dimyristyl thiodipropionate, distearyl thiodipropionate, and ditridecyl thiodipropionate are safe as cosmetic ingredients in the practices of use and concentration given in this safety assessment when formulated to be nonirritating.

Formulation Reading

For formula review, begin with the exact INCI identity and the ingredient group covered by the CIR assessment. If the material is Thiodipropionic Acid and Its Dialkyl Esters, the relevant comparison is whether the intended use aligns with the practices, concentration ranges, and conditions described in the CIR source.

The ingredient hub at Thiodipropionic Acid and Its Dialkyl Esters should carry the substance-level profile. This page is the report-level summary, keeping the conclusion, ingredient scope, and use-context language attached to the CIR source rather than treating the conclusion as a universal permission.

Why This Page Exists

CIR reviews are long documents, and the practical answer is usually buried in the conclusion and the table of current practices. This summary keeps those CIR facts in one indexable page for Thiodipropionic Acid and Its Dialkyl Esters, with source details retained at the bottom for audit.


Source

  • CIR report: Final Safety Assessment of Thiodipropionic Acid and Its Dialkyl Esters as Used in Cosmetics Catherine Diamante1, Monice Zondlo Fiume2, Wilma F. Bergfeld, MD, FACP3, Donald V. Belsito, MD3, Ronald A. Hill, PhD3, Curtis D. Klaassen, PhD3,
  • CIR source file: PRS526.pdf
  • Extraction JSON: CIR Safety Assessment Database
  • Conclusion page in CIR extraction: 12