PEGylated Oils: CIR Safety Assessment Summary
CIR safety assessment summary for PEGylated Oils: ingredients reviewed, panel verdict, use concentration context, conditions, and source citation.
PEGylated Oils appears in a CIR safety assessment covering PEGylated Oils. The panel verdict for the report is safe with restrictions. Summary Reference PEGylated castor oils PEG-30, -33, -35, -36, and -40 castor oil are safe for use in cosmetics at concentrations up to 50% and PEG-30 and -40 hydrogenated castor oil are safe for use at concentrations up to 100% PEG castor oils and PEG hydrogenated castor oils are used as skin-conditioning agents and as surfactants (emulsifying and/or solubilizing agents). Results from animal studies indicate very high acute LD50 values.
| Field | CIR value |
|---|---|
| Primary ingredient | PEGylated Oils |
| CIR verdict | safe with restrictions |
| Report type | Safety Assessment |
| Date | In 1997 |
| Use concentration context | up to 50%; up to 100%; 50%; up to 5% |
| Conditions or carve-outs |
Ingredients Reviewed
The review scope matters because CIR conclusions often apply to an ingredient family rather than a single INCI name. In this report, the ingredient list includes PEGylated Oils.
Safety Conclusion
The conclusion for PEGylated Oils should be read as a CIR panel conclusion, not a regulatory limit. CIR assessments summarize expert-panel safety determinations for cosmetic use, while legal status still depends on the jurisdiction and product category.
For use levels, the report gives this concentration context: up to 50%; up to 100%; 50%; up to 5%. That language is the safe-use context shown for this page.
Conditions
Summary Reference PEGylated castor oils PEG-30, -33, -35, -36, and -40 castor oil are safe for use in cosmetics at concentrations up to 50% and PEG-30 and -40 hydrogenated castor oil are safe for use at concentrations up to 100% PEG castor oils and PEG hydrogenated castor oils are used as skin-conditioning agents and as surfactants (emulsifying and/or solubilizing agents).
Formulation Reading
For formula review, begin with the exact INCI identity and the ingredient group covered by the CIR assessment. If the material is PEGylated Oils, the relevant comparison is whether the intended use aligns with the practices, concentration ranges, and conditions described in the CIR source.
The ingredient hub at PEGylated Oils should carry the substance-level profile. This page is the report-level summary, keeping the conclusion, ingredient scope, and use-context language attached to the CIR source rather than treating the conclusion as a universal permission.
Why This Page Exists
CIR reviews are long documents, and the practical answer is usually buried in the conclusion and the table of current practices. This summary keeps those CIR facts in one indexable page for PEGylated Oils, with source details retained at the bottom for audit.
Source
- CIR report: Safety Assessment of PEGylated Oils as Used in Cosmetics Christina L. Burnett1, Bart Heldreth2, Wilma F. Bergfeld3, Donald V. Belsito3, Ronald A. Hill3, Curtis D. Klaassen3, Daniel C. Liebler3, James G. Marks Jr3, Ronald C. Shank3,
- CIR source file: PRS622.pdf
- Extraction JSON: CIR Safety Assessment Database
- Conclusion page in CIR extraction: 4