CIR Review Summary May 6, 2026 3 min read

Parabens: CIR Safety Assessment Summary

CIR safety assessment summary for Parabens: ingredients reviewed, panel verdict, use concentration context, conditions, and source citation.

Parabens appears in a CIR safety assessment covering Parabens. The panel verdict for the report is safe with restrictions. Reference Methylparaben, Ethylparaben, Propylparaben, and Butylparaben Safe as cosmetic ingredients in the present practices of use 198446 Benzylparaben Available data are insufficient to support the safety 198647 Isobutylparaben and Isopropylparaben Safe as cosmetic ingredients in the present practices of use 199548 Methylparaben, Ethylparaben, Propylparaben, Butylparaben, Benzylparaben, Isopropylparaben, and. (continued) Ingredient CAS No.

FieldCIR value
Primary ingredientParabens
CIR verdictsafe with restrictions
Report typeSafety Assessment
Date1 In 2017
CAS numbers99-76-3, 26112-07-2, 5026-62-0, 120-47-8, 36457-19-9, 35285-68-8, 4191-73-5, 94-13-3, 84930-16-5, 35285-69-9, 4247-02-3, 84930-15-4, 94-26-8, 38566-94-8, 36457-20-2, 94-18-8, 99-96-7, 69959-44-0, 16782-08-4, 685080-04-2
Use concentration contextup to 0.9%; 0.8%; 0.65%; at 1%
Conditions or carve-outs

Ingredients Reviewed

The review scope matters because CIR conclusions often apply to an ingredient family rather than a single INCI name. In this report, the ingredient list includes Parabens.

Safety Conclusion

The conclusion for Parabens should be read as a CIR panel conclusion, not a regulatory limit. CIR assessments summarize expert-panel safety determinations for cosmetic use, while legal status still depends on the jurisdiction and product category.

For use levels, the report gives this concentration context: up to 0.9%; 0.8%; 0.65%; at 1%. That language is the safe-use context shown for this page.

Conditions

Reference Methylparaben, Ethylparaben, Propylparaben, and Butylparaben Safe as cosmetic ingredients in the present practices of use 198446 Benzylparaben Available data are insufficient to support the safety 198647 Isobutylparaben and Isopropylparaben Safe as cosmetic ingredients in the present practices of use 199548 Methylparaben, Ethylparaben, Propylparaben, Butylparaben, Benzylparaben, Isopropylparaben, and.

Formulation Reading

For formula review, begin with the exact INCI identity and the ingredient group covered by the CIR assessment. If the material is Parabens, the relevant comparison is whether the intended use aligns with the practices, concentration ranges, and conditions described in the CIR source.

The ingredient hub at Parabens should carry the substance-level profile. This page is the report-level summary, keeping the conclusion, ingredient scope, and use-context language attached to the CIR source rather than treating the conclusion as a universal permission.

Why This Page Exists

CIR reviews are long documents, and the practical answer is usually buried in the conclusion and the table of current practices. This summary keeps those CIR facts in one indexable page for Parabens, with source details retained at the bottom for audit.


Source

  • CIR report: Amended Safety Assessment of Parabens as Used in Cosmetics Priya Cherian1, Jinqiu Zhu2, Wilma F. Bergfeld3, Donald V. Belsito3, Ronald A. Hill4, Curtis D. Klaassen3, Daniel C. Liebler3, James G. Marks, Jr.3, Ronald C. Shank3, Thomas J. Slag
  • CIR source file: PRS746.pdf
  • Extraction JSON: CIR Safety Assessment Database
  • Conclusion page in CIR extraction: 5