CIR Review Summary May 6, 2026 3 min read

N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate: CIR Safety Assessment Summary

CIR safety assessment summary for N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate: ingredients reviewed, panel verdict, use concentration context, cond.

N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate appears in a CIR safety assessment covering N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate. The panel verdict for the report is safe. On the basis of the animal and clinical data presented in this report, the CIR Expert Panel concludes that N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate is safe as a cosmetic ingredient in the present practices of use and concentration.

FieldCIR value
Primary ingredientN,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate
CIR verdictsafe
Report typeFinal Report
Date1992
CAS numbers54381-16-7, 57524-61-5, 58262-44-5
Use concentration contextpresent practices of use and concentration described in the safety assessment
Conditions or carve-outs

Ingredients Reviewed

The review scope matters because CIR conclusions often apply to an ingredient family rather than a single INCI name. In this report, the ingredient list includes N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate.

Safety Conclusion

The conclusion for N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate should be read as a CIR panel conclusion, not a regulatory limit. CIR assessments summarize expert-panel safety determinations for cosmetic use, while legal status still depends on the jurisdiction and product category.

For use levels, the report gives this concentration context: present practices of use and concentration described in the safety assessment. That language is the safe-use context shown for this page.

Conditions

On the basis of the animal and clinical data presented in this report, the CIR Expert Panel concludes that N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate is safe as a cosmetic ingredient in the present practices of use and concentration.

Formulation Reading

For formula review, begin with the exact INCI identity and the ingredient group covered by the CIR assessment. If the material is N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate, the relevant comparison is whether the intended use aligns with the practices, concentration ranges, and conditions described in the CIR source.

The ingredient hub at N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate should carry the substance-level profile. This page is the report-level summary, keeping the conclusion, ingredient scope, and use-context language attached to the CIR source rather than treating the conclusion as a universal permission.

Why This Page Exists

CIR reviews are long documents, and the practical answer is usually buried in the conclusion and the table of current practices. This summary keeps those CIR facts in one indexable page for N,N-Bis(2-Hydroxyethyl)-p-Phenylenediamine Sulfate, with source details retained at the bottom for audit.


Source

  • CIR report: Final Report on the Safety Assessment of N,N-Bis(Hydroxyethyl)-p-Phenylenediamine Sulfate
  • CIR source file: pr115.pdf
  • Extraction JSON: Source documentation archived.
  • Conclusion page in CIR extraction: 14