Methenamine: CIR Safety Assessment Summary
CIR safety assessment summary for Methenamine: ingredients reviewed, panel verdict, use concentration context, conditions, and source citation.
Methenamine appears in a CIR safety assessment covering Methenamine. The panel verdict for the report is Safe with qualification. On the basis of the animal and clinical data presented in this report, the CIR Expert Panel concludes that Methenamine is safe for cosmetic use at concentrations not to exceed 0.16% in formulation. It cannot be concluded that Methenamine is safe for use in cosmetic products intended to be aerosolized.
| Field | CIR value |
|---|---|
| Primary ingredient | Methenamine |
| CIR verdict | Safe with qualification |
| Report type | Final Report |
| Date | 1992 |
| CAS numbers | 100-97-0 |
| Use concentration context | |
| Conditions or carve-outs |
Ingredients Reviewed
The review scope matters because CIR conclusions often apply to an ingredient family rather than a single INCI name. In this report, the ingredient list includes Methenamine.
Safety Conclusion
The conclusion for Methenamine should be read as a CIR panel conclusion, not a regulatory limit. CIR assessments summarize expert-panel safety determinations for cosmetic use, while legal status still depends on the jurisdiction and product category.
For use levels, the report gives this concentration context: . That language is the safe-use context shown for this page.
Conditions
On the basis of the animal and clinical data presented in this report, the CIR Expert Panel concludes that Methenamine is safe for cosmetic use at concentrations not to exceed 0.16% in formulation.
Formulation Reading
For formula review, begin with the exact INCI identity and the ingredient group covered by the CIR assessment. If the material is Methenamine, the relevant comparison is whether the intended use aligns with the practices, concentration ranges, and conditions described in the CIR source.
The ingredient hub at Methenamine should carry the substance-level profile. This page is the report-level summary, keeping the conclusion, ingredient scope, and use-context language attached to the CIR source rather than treating the conclusion as a universal permission.
Why This Page Exists
CIR reviews are long documents, and the practical answer is usually buried in the conclusion and the table of current practices. This summary keeps those CIR facts in one indexable page for Methenamine, with source details retained at the bottom for audit.
Source
- CIR report: Final Report on the Safety Assessment of Methenamine
- CIR source file: pr108.pdf
- Extraction JSON: Source documentation archived.
- Conclusion page in CIR extraction: 26