CIR Review Summary May 6, 2026 3 min read

Keratin and Keratin-Derived Ingredients: CIR Safety Assessment Summary

CIR safety assessment summary for Keratin and Keratin-Derived Ingredients: ingredients reviewed, panel verdict, use concentration context, conditions, and.

Keratin and Keratin-Derived Ingredients appears in a CIR safety assessment covering Keratin and Keratin-Derived Ingredients. The panel verdict for the report is safe. The Panel concluded the following keratin-derived ingredients are safe in cosmetics in the present practices of use and concentration as described in this safety assessment. Hydrolyzed Keratin Hydrolyzed Hair Keratin Hydrolyzed Oxidized Keratin* Hydrolyzed Sulfonated Keratin* Keratin Oxidized Keratin* Soluble Keratin Sulfonated Keratin* *Not reported to be in current use.

FieldCIR value
Primary ingredientKeratin and Keratin-Derived Ingredients
CIR verdictsafe
Report typeSafety Assessment
Date2021
CAS numbers65997-21-9, 73049-73-7, 69430-36-0, 1142948-22-8, 1119233-83-8, 169799-44-4, 68238-35-7, 143819-61-8, 1119232-93-7
Conditions or carve-outsNot reported to be in current use

Ingredients Reviewed

The review scope matters because CIR conclusions often apply to an ingredient family rather than a single INCI name. In this report, the ingredient list includes Keratin and Keratin-Derived Ingredients.

Safety Conclusion

The conclusion for Keratin and Keratin-Derived Ingredients should be read as a CIR panel conclusion, not a regulatory limit. CIR assessments summarize expert-panel safety determinations for cosmetic use, while legal status still depends on the jurisdiction and product category.

Conditions

Not reported to be in current use

Formulation Reading

For formula review, begin with the exact INCI identity and the ingredient group covered by the CIR assessment. If the material is Keratin and Keratin-Derived Ingredients, the relevant comparison is whether the intended use aligns with the practices, concentration ranges, and conditions described in the CIR source.

The ingredient hub at Keratin and Keratin-Derived Ingredients should carry the substance-level profile. This page is the report-level summary, keeping the conclusion, ingredient scope, and use-context language attached to the CIR source rather than treating the conclusion as a universal permission.

Why This Page Exists

CIR reviews are long documents, and the practical answer is usually buried in the conclusion and the table of current practices. This summary keeps those CIR facts in one indexable page for Keratin and Keratin-Derived Ingredients, with source details retained at the bottom for audit.

Review Notes

The conservative reading is to keep Keratin and Keratin-Derived Ingredients tied to the exact CIR report listed below. The ingredient family, panel conclusion, date, and any use-condition language belong together. A shorter ingredient-page snippet would lose that context.

This page gives the search-level answer while preserving the source-level caveat: CIR safety language is a panel assessment for cosmetic practices of use, not a universal legal permission across every jurisdiction or product category.


Source

  • CIR report: Safety Assessment of Keratin and Keratin-Derived Ingredients as Used in Cosmetics Christina L. Burnett*, Wilma F. Bergfeld**, Donald V. Belsito**, Ronald A. Hill***, Curtis D. Klaassen**, Daniel C. Liebler**,
  • CIR source file: PRS713.pdf
  • Extraction JSON: Source documentation archived.
  • Conclusion page in CIR extraction: 13