CIR Review Summary May 6, 2026 3 min read

Hydroxyethyl-3,4-Methylenedioxyaniline HCl: CIR Safety Assessment Summary

CIR safety assessment summary for Hydroxyethyl-3,4-Methylenedioxyaniline HCl: ingredients reviewed, panel verdict, use concentration context, conditions,.

Hydroxyethyl-3,4-Methylenedioxyaniline HCl appears in a CIR safety assessment covering Hydroxyethyl-3,4-Methylenedioxyaniline HCl. The panel verdict for the report is safe. The Expert Panel for Cosmetic Ingredient Safety concluded that Hydroxyethyl-3,4-Methylenedioxyaniline HCl is safe for use as a hair dye ingredient in the present practices of use and concentrations described in this safety assessment. Scott et al.

FieldCIR value
Primary ingredientHydroxyethyl-3,4-Methylenedioxyaniline HCl
CIR verdictsafe
Report typeSafety Assessment
Date10 The 2016
CAS numbers94158-14-2
Use concentration contextpresent practices of use and concentration described in the safety assessment
Conditions or carve-outs

Ingredients Reviewed

The review scope matters because CIR conclusions often apply to an ingredient family rather than a single INCI name. In this report, the ingredient list includes Hydroxyethyl-3,4-Methylenedioxyaniline HCl.

Safety Conclusion

The conclusion for Hydroxyethyl-3,4-Methylenedioxyaniline HCl should be read as a CIR panel conclusion, not a regulatory limit. CIR assessments summarize expert-panel safety determinations for cosmetic use, while legal status still depends on the jurisdiction and product category.

For use levels, the report gives this concentration context: present practices of use and concentration described in the safety assessment. That language is the safe-use context shown for this page.

Conditions

The Expert Panel for Cosmetic Ingredient Safety concluded that Hydroxyethyl-3,4-Methylenedioxyaniline HCl is safe for use as a hair dye ingredient in the present practices of use and concentrations described in this safety assessment.

Formulation Reading

For formula review, begin with the exact INCI identity and the ingredient group covered by the CIR assessment. If the material is Hydroxyethyl-3,4-Methylenedioxyaniline HCl, the relevant comparison is whether the intended use aligns with the practices, concentration ranges, and conditions described in the CIR source.

The ingredient hub at Hydroxyethyl-3,4-Methylenedioxyaniline HCl should carry the substance-level profile. This page is the report-level summary, keeping the conclusion, ingredient scope, and use-context language attached to the CIR source rather than treating the conclusion as a universal permission.

Why This Page Exists

CIR reviews are long documents, and the practical answer is usually buried in the conclusion and the table of current practices. This summary keeps those CIR facts in one indexable page for Hydroxyethyl-3,4-Methylenedioxyaniline HCl, with source details retained at the bottom for audit.


Source

  • CIR report: Safety Assessment of Hydroxyethyl-3,4-Methylenedioxyaniline HCl as Used in Cosmetics Laura N Scott, MS1, Wilma F. Bergfeld, MD FACP2, Donald V. Belsito, MD2, Ronald A. Hill, PhD3, Curtis D. Klaassen, PhD2, Daniel C. Liebler, PhD2, James G.
  • CIR source file: PRS732.pdf
  • Extraction JSON: CIR Safety Assessment Database
  • Conclusion page in CIR extraction: 14