CIR Review Summary May 6, 2026 3 min read

HDI/Trimethylol Hexyllactone Crosspolymer: CIR Safety Assessment Summary

CIR safety assessment summary for HDI/Trimethylol Hexyllactone Crosspolymer: ingredients reviewed, panel verdict, use concentration context, conditions, a.

HDI/Trimethylol Hexyllactone Crosspolymer appears in a CIR safety assessment covering HDI/Trimethylol Hexyllactone Crosspolymer, Bis-C16-20 Isoalkoxy TMHDI/PEG-90 Copolymer, Bis-Hydroxyethyl Acrylate Poly(1,4-Butanediol)-9/TMHDI Copolymer, , Bis-Lauryl Cocaminopropylamine/HDI/PEG-100 Copolymer, Bis-Methoxy PEG-10 Dimethyl MEA/HDI/Bis-PEG-10 Dimethicone Copolymer, 1,4-Butanediol/Succinic Acid/Adipic Acid/HDI Copolymer, Cholesterol/HDI/Pullulan Copolymer, and 4 more. The panel verdict for the report is 17 ingredients safe; 2 insufficient data. The CIR Expert Panel concluded that the following 17 HDI polymers are safe in cosmetics in the present practices of use and concentration described in this safety assessment: HDI/Trimethylol Hexyllactone Crosspolymer, Bis-C16-20 Isoalkoxy TMHDI/PEG-90 Copolymer, Bis-Isostearyl 1,4-Butanediol/HDI/Hydrogenated Dimer Dilinoleyl Alcohol Copolymer, Bis-Lauryl Cocaminopropylamine/HDI/PEG-100 Copolymer, Bis-Methoxy PEG-10.

FieldCIR value
Primary ingredientHDI/Trimethylol Hexyllactone Crosspolymer
CIR verdict17 ingredients safe; 2 insufficient data
Report typeFinal Report
DateJuly 7, 2016
CAS numbers119553-67-2, 103777-69-1, 302791-95-3, 1268856-56-9
Use concentration contextpresent practices of use and concentration described in the safety assessment
Conditions or carve-outs

Ingredients Reviewed

The review scope matters because CIR conclusions often apply to an ingredient family rather than a single INCI name. In this report, the ingredient list includes HDI/Trimethylol Hexyllactone Crosspolymer, Bis-C16-20 Isoalkoxy TMHDI/PEG-90 Copolymer, Bis-Hydroxyethyl Acrylate Poly(1,4-Butanediol)-9/TMHDI Copolymer, Bis-Isostearyl 1,4-Butanediol/HDI/Hydrogenated Dimer Dilinoleyl Alcohol Copolymer, Bis-Lauryl Cocaminopropylamine/HDI/PEG-100 Copolymer, Bis-Methoxy PEG-10 Dimethyl MEA/HDI/Bis-PEG-10 Dimethicone Copolymer, 1,4-Butanediol/Succinic Acid/Adipic Acid/HDI Copolymer, Cholesterol/HDI/Pullulan Copolymer, and 4 more.

Safety Conclusion

The conclusion for HDI/Trimethylol Hexyllactone Crosspolymer should be read as a CIR panel conclusion, not a regulatory limit. CIR assessments summarize expert-panel safety determinations for cosmetic use, while legal status still depends on the jurisdiction and product category.

For use levels, the report gives this concentration context: present practices of use and concentration described in the safety assessment. That language is the safe-use context shown for this page.

Conditions

The CIR Expert Panel concluded that the following 17 HDI polymers are safe in cosmetics in the present practices of use and concentration described in this safety assessment: HDI/Trimethylol Hexyllactone Crosspolymer, Bis-C16-20 Isoalkoxy TMHDI/PEG-90 Copolymer, Bis-Isostearyl 1,4-Butanediol/HDI/Hydrogenated Dimer Dilinoleyl Alcohol Copolymer, Bis-Lauryl Cocaminopropylamine/HDI/PEG-100 Copolymer, Bis-Methoxy PEG-10.

Formulation Reading

For formula review, begin with the exact INCI identity and the ingredient group covered by the CIR assessment. If the material is HDI/Trimethylol Hexyllactone Crosspolymer, the relevant comparison is whether the intended use aligns with the practices, concentration ranges, and conditions described in the CIR source.

The ingredient hub at HDI/Trimethylol Hexyllactone Crosspolymer should carry the substance-level profile. This page is the report-level summary, keeping the conclusion, ingredient scope, and use-context language attached to the CIR source rather than treating the conclusion as a universal permission.

Why This Page Exists

CIR reviews are long documents, and the practical answer is usually buried in the conclusion and the table of current practices. This summary keeps those CIR facts in one indexable page for HDI/Trimethylol Hexyllactone Crosspolymer, with source details retained at the bottom for audit.


Source

  • CIR report: Safety Assessment of Hexamethylene Diisocyanate (HDI) Polymers as Used in Cosmetics
  • CIR source file: FR704.pdf
  • Extraction JSON: Source documentation archived.
  • Conclusion page in CIR extraction: 10