CIR Review Summary May 6, 2026 3 min read

Ceramides: CIR Safety Assessment Summary

CIR safety assessment summary for Ceramides: ingredients reviewed, panel verdict, use concentration context, conditions, and source citation.

Ceramides appears in a CIR safety assessment covering Ceramides. The panel verdict for the report is safe with restrictions. The Panel concluded that the following ceramide ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment: Ceramide 1 [retired] Ceramide 2 [retired] Burnett et al 11S Ceramide 3 [retired] Ceramide 4* [retired] Ceramide 5 [retired] Ceramide 1A [retired] Ceramide 6 II [retired] Ceramide AP Ceramide EOP Ceramide EOS Ceramide NP Ceramide NG* Ceramide NS.

FieldCIR value
Primary ingredientCeramides
CIR verdictsafe with restrictions
Report typeSafety Assessment
Date2020
Conditions or carve-outsNot reported to be in current use

Ingredients Reviewed

The review scope matters because CIR conclusions often apply to an ingredient family rather than a single INCI name. In this report, the ingredient list includes Ceramides.

Safety Conclusion

The conclusion for Ceramides should be read as a CIR panel conclusion, not a regulatory limit. CIR assessments summarize expert-panel safety determinations for cosmetic use, while legal status still depends on the jurisdiction and product category.

Conditions

Not reported to be in current use

Formulation Reading

For formula review, begin with the exact INCI identity and the ingredient group covered by the CIR assessment. If the material is Ceramides, the relevant comparison is whether the intended use aligns with the practices, concentration ranges, and conditions described in the CIR source.

The ingredient hub at Ceramides should carry the substance-level profile. This page is the report-level summary, keeping the conclusion, ingredient scope, and use-context language attached to the CIR source rather than treating the conclusion as a universal permission.

Why This Page Exists

CIR reviews are long documents, and the practical answer is usually buried in the conclusion and the table of current practices. This summary keeps those CIR facts in one indexable page for Ceramides, with source details retained at the bottom for audit.

Review Notes

The conservative reading is to keep Ceramides tied to the exact CIR report listed below. The ingredient family, panel conclusion, date, and any use-condition language belong together. A shorter ingredient-page snippet would lose that context.

This page gives the search-level answer while preserving the source-level caveat: CIR safety language is a panel assessment for cosmetic practices of use, not a universal legal permission across every jurisdiction or product category.

The source section is intentionally specific. It keeps Ceramides connected to the CIR report file and conclusion page so the summary remains an audit-friendly report page instead of a loose ingredient claim.


Source

  • CIR report: Safety Assessment of Ceramides as Used in Cosmetics Christina L. Burnett*, Ivan J. Boyer**, Wilma F. Bergfeld***, Donald V. Belsito***, Ronald A. Hill***, Curtis D. Klaassen***, Daniel C. Liebler***, James G. Marks Jr***, Ronald C. Shank***
  • CIR source file: PRS674.pdf
  • Extraction JSON: Source documentation archived.
  • Conclusion page in CIR extraction: 7