α-Amino Acids: CIR Safety Assessment Summary
CIR safety assessment summary for α-Amino Acids: ingredients reviewed, panel verdict, use concentration context, conditions, and source citation.
α-Amino Acids appears in a CIR safety assessment covering α-Amino Acids. The panel verdict for the report is safe with restrictions. The Panel concluded that a-amino acids, listed below, are safe in the present practices of use and concentration in cosmetics. Alanine Arginine Arginine HCl Asparagine Aspartic Acid Calcium Aspartate* Calcium Glycinate Cysteine Cysteine HCl Cystine Table 6.
| Field | CIR value |
|---|---|
| Primary ingredient | α-Amino Acids |
| CIR verdict | safe with restrictions |
| Report type | Safety Assessment |
| Date | 1101 |
| CAS numbers | 56-41-7, 74-79-3, 1119-34-2, 70-47-3, 5794-13-8, 56-84-8, 5598-53-8, 1115-63-5, 14007-45-5, 21059-46-1, 2068-80-6, 18962-61-3, 52-90-4, 52-89-1, 56-89-3, 56-86-0, 16177-21-2, 26106-04-3, 56-85-9, 56-40-6, 35947-07-0, 14783-68-7, 71-00-1, 645-35-2, 5934-29-2, 73-32-5, 61-90-5, 56-87-1 |
| Use concentration context | 5%; 1.4%; 0.2%; 0.1% |
| Conditions or carve-outs |
Ingredients Reviewed
The review scope matters because CIR conclusions often apply to an ingredient family rather than a single INCI name. In this report, the ingredient list includes α-Amino Acids.
Safety Conclusion
The conclusion for α-Amino Acids should be read as a CIR panel conclusion, not a regulatory limit. CIR assessments summarize expert-panel safety determinations for cosmetic use, while legal status still depends on the jurisdiction and product category.
For use levels, the report gives this concentration context: 5%; 1.4%; 0.2%; 0.1%. That language is the safe-use context shown for this page.
Conditions
The Panel concluded that a-amino acids, listed below, are safe in the present practices of use and concentration in cosmetics.
Formulation Reading
For formula review, begin with the exact INCI identity and the ingredient group covered by the CIR assessment. If the material is α-Amino Acids, the relevant comparison is whether the intended use aligns with the practices, concentration ranges, and conditions described in the CIR source.
The ingredient hub at α-Amino Acids should carry the substance-level profile. This page is the report-level summary, keeping the conclusion, ingredient scope, and use-context language attached to the CIR source rather than treating the conclusion as a universal permission.
Why This Page Exists
CIR reviews are long documents, and the practical answer is usually buried in the conclusion and the table of current practices. This summary keeps those CIR facts in one indexable page for α-Amino Acids, with source details retained at the bottom for audit.
Review Notes
The conservative reading is to keep α-Amino Acids tied to the exact CIR report listed below. The ingredient family, panel conclusion, date, and any use-condition language belong together. A shorter ingredient-page snippet would lose that context.
This page gives the search-level answer while preserving the source-level caveat: CIR safety language is a panel assessment for cosmetic practices of use, not a universal legal permission across every jurisdiction or product category.
Source
- CIR report: Safety Assessment of α-Amino Acids as Used in Cosmetics Christina L. Burnett1, Bart Heldreth2, Wilma F. Bergfeld3, Donald V. Belsito3, Ronald A. Hill3, Curtis D. Klaassen3, Daniel C. Liebler3, James G. Marks Jr3, Ronald C. Shank3,
- CIR source file: PRS607.pdf
- Extraction JSON: CIR Safety Assessment Database
- Conclusion page in CIR extraction: 19