Alkane Diols: CIR Safety Assessment Summary
CIR safety assessment summary for Alkane Diols: ingredients reviewed, panel verdict, use concentration context, conditions, and source citation.
Alkane Diols appears in a CIR safety assessment covering Alkane Diols. The panel verdict for the report is safe with restrictions. The Expert Panel for Cosmetic Ingredient Safety concluded that the following 7 ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment: Propanediol Methylpropanediol 1,5-Pentanediol* Butyl Ethyl Propanediol Hexanediol Isopentyldiol 1,10-Decanediol *Not reported to be in current use.
| Field | CIR value |
|---|---|
| Primary ingredient | Alkane Diols |
| CIR verdict | safe with restrictions |
| Report type | Safety Assessment |
| Date | Toxicology 2024 |
| CAS numbers | 504-63-2, 110-63-4, 513-85-9, 111-29-5, 629-11-8, 629-41-4, 112-47-0, 2163-42-0, 115-84-4, 2568-33-4 |
| Use concentration context | present practices of use and concentration described in the safety assessment |
| Conditions or carve-outs | Not reported to be in current use |
Ingredients Reviewed
The review scope matters because CIR conclusions often apply to an ingredient family rather than a single INCI name. In this report, the ingredient list includes Alkane Diols.
Safety Conclusion
The conclusion for Alkane Diols should be read as a CIR panel conclusion, not a regulatory limit. CIR assessments summarize expert-panel safety determinations for cosmetic use, while legal status still depends on the jurisdiction and product category.
For use levels, the report gives this concentration context: present practices of use and concentration described in the safety assessment. That language is the safe-use context shown for this page.
Conditions
Not reported to be in current use
Formulation Reading
For formula review, begin with the exact INCI identity and the ingredient group covered by the CIR assessment. If the material is Alkane Diols, the relevant comparison is whether the intended use aligns with the practices, concentration ranges, and conditions described in the CIR source.
The ingredient hub at Alkane Diols should carry the substance-level profile. This page is the report-level summary, keeping the conclusion, ingredient scope, and use-context language attached to the CIR source rather than treating the conclusion as a universal permission.
Why This Page Exists
CIR reviews are long documents, and the practical answer is usually buried in the conclusion and the table of current practices. This summary keeps those CIR facts in one indexable page for Alkane Diols, with source details retained at the bottom for audit.
Review Notes
The conservative reading is to keep Alkane Diols tied to the exact CIR report listed below. The ingredient family, panel conclusion, date, and any use-condition language belong together. A shorter ingredient-page snippet would lose that context.
This page gives the search-level answer while preserving the source-level caveat: CIR safety language is a panel assessment for cosmetic practices of use, not a universal legal permission across every jurisdiction or product category.
Source
- CIR report: Safety Assessment of Alkane Diols as Used in Cosmetics Laura N. Scott*, Monice Fiume**, Wilma F. Bergfeld***, Donald V. Belsito***, Ronald A. Hill****, Curtis D. Klaassen***, Daniel C. Liebler****, James G. Marks Jr****, Ronald C. Shank****
- CIR source file: done.pdf
- Extraction JSON: Source documentation archived.
- Conclusion page in CIR extraction: 57