CIR Review Summary May 6, 2026 3 min read

Acid Orange 31 Acid Orange 3 is a nitro color used as a hair colorant. Short-term animal studies showed no toxicity at oral exposures less: CIR Safety Assessment Summary

CIR safety assessment summary for Acid Orange 31 Acid Orange 3 is a nitro color used as a hair colorant. Short-term animal studies showed no toxicity at.

appears in a CIR safety assessment covering . The panel verdict for the report is safe. On the basis of the animal and clinical data included in this report, the CIR Expert Panel concludes ~hat Acid Orange 3 is safe for use in hair dye formulations at concentrations <0.2%.

FieldCIR value
Primary ingredient
CIR verdictsafe
Report typeFinal Report
Date3 February 2000
CAS numbers6373-74-6
Use concentration context
Conditions or carve-outs

Ingredients Reviewed

The review scope matters because CIR conclusions often apply to an ingredient family rather than a single INCI name. In this report, the ingredient list includes .

Safety Conclusion

The conclusion for should be read as a CIR panel conclusion, not a regulatory limit. CIR assessments summarize expert-panel safety determinations for cosmetic use, while legal status still depends on the jurisdiction and product category.

For use levels, the report gives this concentration context: . That language is the safe-use context shown for this page.

Conditions

On the basis of the animal and clinical data included in this report, the CIR Expert Panel concludes ~hat Acid Orange 3 is safe for use in hair dye formulations at concentrations <0.2%.

Formulation Reading

For formula review, begin with the exact INCI identity and the ingredient group covered by the CIR assessment. If the material is , the relevant comparison is whether the intended use aligns with the practices, concentration ranges, and conditions described in the CIR source.

The ingredient hub at should carry the substance-level profile. This page is the report-level summary, keeping the conclusion, ingredient scope, and use-context language attached to the CIR source rather than treating the conclusion as a universal permission.

Why This Page Exists

CIR reviews are long documents, and the practical answer is usually buried in the conclusion and the table of current practices. This summary keeps those CIR facts in one indexable page for Acid Orange 31 Acid Orange 3 is a nitro color used as a hair colorant. Short-term animal studies showed no toxicity at oral exposures less, with source details retained at the bottom for audit.


Source

  • CIR report: Final Report on the Safety Assessment of Acid Orange 31 Acid Orange 3 is a nitro color used as a hair colorant. Short-term animal studies showed no toxicity at oral exposures less than 1.5 g/kg in rats and 1.0 g/kg in mice. Dermal exposure
  • CIR source file: pr24.pdf
  • Extraction JSON: Source documentation archived.
  • Conclusion page in CIR extraction: 8