1,2-Glycols: CIR Safety Assessment Summary
CIR safety assessment summary for 1,2-Glycols: ingredients reviewed, panel verdict, use concentration context, conditions, and source citation.
1,2-Glycols appears in a CIR safety assessment covering 1,2-Glycols. The panel verdict for the report is safe. The CIR Expert Panel concluded that the following cosmetic ingredients are safe in the present practices of use and concentration described in this safety assessment: caprylyl glycol arachidyl glycol* cetyl glycol* hexacosyl glycol* lauryl glycol* myristyl glycol* octacosanyl glycol* stearyl glycol* decylene glycol pentylene glycol 1,2-butanediol* 1,2-hexanediol C14-18 glycol* C15-18.
| Field | CIR value |
|---|---|
| Primary ingredient | 1,2-Glycols |
| CIR verdict | safe |
| Report type | Safety Assessment |
| Date | In 2010 |
| CAS numbers | 39825-93-9, 6920-24-7, 1119-87-5, 21129-09-9, 97338-11-9, 20294-76-2, 1117-86-8, 1119-86-4, 5343-92-0, 584-03-2, 6920-22-5, 70750-40-2, 92128-52-4 |
| Conditions or carve-outs |
Ingredients Reviewed
The review scope matters because CIR conclusions often apply to an ingredient family rather than a single INCI name. In this report, the ingredient list includes 1,2-Glycols.
Safety Conclusion
The conclusion for 1,2-Glycols should be read as a CIR panel conclusion, not a regulatory limit. CIR assessments summarize expert-panel safety determinations for cosmetic use, while legal status still depends on the jurisdiction and product category.
Conditions
The CIR Expert Panel concluded that the following cosmetic ingredients are safe in the present practices of use and concentration described in this safety assessment: caprylyl glycol arachidyl glycol* cetyl glycol* hexacosyl glycol* lauryl glycol* myristyl glycol* octacosanyl glycol* stearyl glycol* decylene glycol pentylene glycol 1,2-butanediol* 1,2-hexanediol C14-18 glycol* C15-18.
Formulation Reading
For formula review, begin with the exact INCI identity and the ingredient group covered by the CIR assessment. If the material is 1,2-Glycols, the relevant comparison is whether the intended use aligns with the practices, concentration ranges, and conditions described in the CIR source.
The ingredient hub at 1,2-Glycols should carry the substance-level profile. This page is the report-level summary, keeping the conclusion, ingredient scope, and use-context language attached to the CIR source rather than treating the conclusion as a universal permission.
Why This Page Exists
CIR reviews are long documents, and the practical answer is usually buried in the conclusion and the table of current practices. This summary keeps those CIR facts in one indexable page for 1,2-Glycols, with source details retained at the bottom for audit.
Source
- CIR report: Safety Assessment of 1,2-Glycols as Used in Cosmetics Wilbur Johnson, Jr1, Wilma F. Bergfeld2, Donald V. Belsito2, Ronald A. Hill1, Curtis D. Klaassen2, Daniel Liebler2, James G. Marks, Jr2, Ronald C. Shank2, Thomas J. Slaga2,
- CIR source file: PRS576.pdf
- Extraction JSON: CIR Safety Assessment Database
- Conclusion page in CIR extraction: 19