Food Safety Substance

E450IE450I

E450I (E450I) is a food additive with Approved in the EU, GRAS in the US, and data from 6 regulatory sources.

CAS 7758-16-9 E450I Indexable evidence set

FDA

GRAS

ADI / TDI

ADI 40 mg/kg bw

Codex

0 row(s)

SOURCE D1 identity resolution e number aliases | Food Additives | dsstox identifiers | 6 matched regulatory source group(s)

Substance Identity

Resolved identifiers used to render this food-safety record.

Substance name

E450I

CAS

7758-16-9

E-number

E450I

PubChem CID

24451

Evidence tier

Indexable evidence set (13)

SOURCE EU Commission EU Food Contact Materials

EU FCM Substances

EU food-contact material rows and migration-limit fields.

Jurisdiction	FCM no.	Ref no.	Substance	Use	SML	Regulation
European Union	-	-	disodium pyrophosphate	-	-	Regulation (EC) No 450/2009, Register v1.1

SOURCE JECFA JECFA ADI

JECFA ADI Values

JECFA ADI records and evaluation years.

Jurisdiction	Chemical name	JECFA no.	CAS	ADI	ADI upper	Function	Evaluation year
JECFA	DISODIUM PYROPHOSPHATE	-	7758-16-9	no_data	-	ACIDITY_REGULATOR, RAISING_AGENT, SEQUESTRANT	1982

SOURCE ingredients ghs classifications

Cross-Reference to Cosmetics / Chemicals / Pharma

Same-CAS public rows from adjacent Roots verticals where available.

SOURCE Cross-vertical comparison ingredients | ghs classifications

Cross-Vertical Regulatory Divergence

This substance has different regulatory treatment across food, cosmetics, and industrial use.

CosmeticsDisodium PyrophosphateEU status: permitted Industrial / GHSWarningEuropean Chemicals Agency (ECHA)

SOURCE FAQPage JSON-LD public food renderer rows

Frequently Asked Questions

Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.

What is E450I used for in food?

E450I appears in food-use rows as: emulsifier|stabilizer.

Is E450I / E450I safe?

This page does not assign a standalone safety verdict; it renders public regulatory evidence. ADI/reference value: ADI 40 mg/kg bw. EU status evidence: Approved. US/FDA evidence: GRAS.

What is the ADI for E450I?

E450I has this ADI/reference value in the food-safety tables: ADI 40 mg/kg bw. Source: food_additives.

Is E450I also used in cosmetics?

E450I has a same-CAS cosmetics cross-reference: Disodium Pyrophosphate, EU status permitted.