Food Safety Substance

E381E381

E381 (E381) is a food additive with Not currently EU-listed in the EU, GRAS in the US, and data from 6 regulatory sources.

CAS 1185-57-5 E381 Indexable evidence set

FDA

GRAS

ADI / TDI

No ADI/TDI row found

Codex

1 row(s)

SOURCE D1 identity resolution e number aliases | Food Additives | dsstox identifiers | 6 matched regulatory source group(s)

Substance Identity

Resolved identifiers used to render this food-safety record.

Substance name

E381

CAS

1185-57-5

E-number

E381

PubChem CID

118984355

Evidence tier

Indexable evidence set (8)

SOURCE EU Commission FDA | Health Canada | Codex Alimentarius

Multi-Jurisdiction Comparison

Side-by-side status rows for the same resolved substance across public food regulators.

Jurisdiction	Authority	Status	Evidence
European Union	EU Commission	Not currently EU-listed	-
Codex	Codex Alimentarius	Listed	Anticaking agent

SOURCE Codex Alimentarius Codex GSFA

Codex GSFA Status

Codex Alimentarius GSFA permissions and maximum-use rows.

Jurisdiction	INS / E-number	Function	Food category	Max level	Notes
Codex	381	Anticaking agent	14.1.4.3 Concentrates (liquid or solid) for water-based flavoured drinks	10 mg/kg	As iron.

SOURCE JECFA JECFA ADI

JECFA ADI Values

JECFA ADI records and evaluation years.

Jurisdiction	Chemical name	JECFA no.	CAS	ADI	ADI upper	Function	Evaluation year
JECFA	FERRIC AMMONIUM CITRATE	-	1185-57-5	no_data	-	ANTICAKING_AGENT, NUTRIENT_SUPPLEMENT	1985

SOURCE ingredients ghs classifications

Cross-Reference to Cosmetics / Chemicals / Pharma

Same-CAS public rows from adjacent Roots verticals where available.

SOURCE Cross-vertical comparison ingredients | ghs classifications

Cross-Vertical Regulatory Divergence

This substance has different regulatory treatment across food, cosmetics, and industrial use.

CosmeticsFerric Ammonium CitrateEU status: permitted Industrial / GHSWarningEuropean Chemicals Agency (ECHA)

SOURCE FAQPage JSON-LD public food renderer rows

Frequently Asked Questions

Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.

What is E381 used for in food?

E381 appears in food-use rows as: acidity_regulator; Anticaking agent.

Is E381 / E381 safe?

This page does not assign a standalone safety verdict; it renders public regulatory evidence. EU status evidence: Not currently EU-listed. US/FDA evidence: GRAS.

What is the ADI for E381?

No ADI row was found for E381 in the rendered EFSA, food_substances, food_additives, or JECFA tables.

Is E381 also used in cosmetics?

E381 has a same-CAS cosmetics cross-reference: Ferric Ammonium Citrate, EU status permitted.