Food Safety Substance
TocopherolsE306
Tocopherols (E306) is a food additive with PUBLISHED in the EU, GRAS in the US, and data from 7 regulatory sources.
CAS 1406-66-2
E306
antioxidant
Indexable evidence set
FDA
GRAS
ADI / TDI
ADI 0.15 mg/kg bw
Codex
0 row(s)
SOURCE
D1 identity resolution
e number aliases | Food Additives | dsstox identifiers | 7 matched regulatory source group(s)
Substance Identity
Resolved identifiers used to render this food-safety record.
Substance name
Tocopherols
CAS
1406-66-2
E-number
E306
Food category
antioxidant
DTXSID
DTXSID8021357
PubChem CID
14986
Evidence tier
Indexable evidence set (10)
SOURCE
EU Commission
FDA | Health Canada | Codex Alimentarius
Multi-Jurisdiction Comparison
Side-by-side status rows for the same resolved substance across public food regulators.
| Jurisdiction | Authority | Status | Evidence |
|---|---|---|---|
| European Union | EU Commission | PUBLISHED | EU additive listing; Annex II entry |
| Canada | Health Canada | Listed | Preservative |
SOURCE
EU Commission
EU Food Additives | EU Food Additives Database
EU Food Additive Status
EU Commission food-additive listing rows from eu_food_additives.
| Jurisdiction | E-number | Status | Type | Name | Note |
|---|---|---|---|---|---|
| European Union | E306 | PUBLISHED | substanceFAD | Tocopherol-rich extract | - |
SOURCE
EU Commission
EU Annex II Authorised | EU Food Additives Database
EU Annex II Authorised Uses
Authorised additive rows and use conditions from EU Annex II tables.
| Jurisdiction | E-number | Name | INS | Policy item | Note |
|---|---|---|---|---|---|
| European Union | E306 | Tocopherol-rich extract | - | POL-FAD-IMPORT-3081 | - |
Conditions and restrictions
| Jurisdiction | Food category | Restriction | Comment | Source |
|---|---|---|---|---|
| European Union | 13.1 foods for infants and young children | - | For uses in nutrient preparations under the condition that the maximum level in foods mentioned in Part E, points 01.10 and 13.1, of Annex II is not exceeded | EU Annex II Union List |
| European Union | 13.1.1 infant formulae as defined by Regulation (EU) No 609/2013 | ML 10 mg/kg | E 306, E 307, E 308 and E 309 are authorised individually or in combination | EU Annex II Union List |
| European Union | 13.1.2 follow-on formulae as defined by by Regulation (EU) No 609/2013 | ML 10 mg/kg | E 306, E 307, E 308 and E 309 are authorised individually or in combination | EU Annex II Union List |
| European Union | 13.1.3 Processed cereal-based foods and baby foods as defined by Regulation (EU) No 609/2013 | ML 100 mg/kg | only fat-containing cereal-based foods including biscuits and rusks and baby foods | EU Annex II Union List |
| European Union | 2.1 fats and oils essentially free from water (excluding anhydrous milk fat) | quantum satis | except virgin oils and olive oils | EU Food Additives Database |
| European Union | 13.1.1 infant formulae as defined by Regulation (EU) No 609/2013 | ML 10 mg/kg | E 306, E 307, E 308 and E 309 are authorised individually or in combination | EU Food Additives Database |
| European Union | 13.1.2 follow-on formulae as defined by by Regulation (EU) No 609/2013 | ML 10 mg/kg | E 306, E 307, E 308 and E 309 are authorised individually or in combination | EU Food Additives Database |
| European Union | 13.1.3 Processed cereal-based foods and baby foods as defined by Regulation (EU) No 609/2013 | ML 100 mg/kg | only fat-containing cereal-based foods including biscuits and rusks and baby foods | EU Food Additives Database |
| European Union | 13.1 foods for infants and young children | - | For uses in nutrient preparations under the condition that the maximum level in foods mentioned in Part E, points 01.10 and 13.1, of Annex II is not exceeded | EU Food Additives Database |
| European Union | 1.10 Milk-based drinks and similar products intended for young children* | ML 100 mg/l | - | EU Food Additives Database |
SOURCE
Health Canada
Health Canada Status
Health Canada food-additive permissions by functional class and food scope.
| Jurisdiction | Class | Permitted foods | Maximum level | List |
|---|---|---|---|---|
| Canada | Preservative | (a)Dehydrated fish broth; Dehydrated mollusc broth | (a)50 ppm in the reconstituted broth | List of Permitted Preservatives |
| Canada | Preservative | (b)Dried cooked poultry meat | (b)0.03% of the fat content | List of Permitted Preservatives |
| Canada | Preservative | (b.1) (Naming the flavour) essence; (Naming the flavour) extract; (Naming the flavour) flavour | (b.1) Good Manufacturing Practice | List of Permitted Preservatives |
| Canada | Preservative | (c)Fats and oils, except milk fat, olive oil and suet; Lard; Mono- and diglycerides; Shortening | (c)Good Manufacturing Practice | List of Permitted Preservatives |
| Canada | Preservative | (d)Frozen fish fillets; Frozen prepared fish fillets | (d)300 ppm | List of Permitted Preservatives |
| Canada | Preservative | (e)Infant formula | (e)10 ppm in the infant formula as consumed | List of Permitted Preservatives |
| Canada | Preservative | (f)Oils used in infant formula | (f)Good Manufacturing Practice | List of Permitted Preservatives |
| Canada | Preservative | (g)Olive oil | (g)Only α-tocopherol may be used, in an amount sufficient to replace that lost during refining, and the addition must be declared on the label. | List of Permitted Preservatives |
| Canada | Preservative | (h)Unstandardized foods, except unstandardized preparations of meat or meat by-product, fish or meat (as defined in section B.21.002 of the *Food and Drug Regulations*) or poultry meat or poultry meat by-product | (h)Good Manufacturing Practice | List of Permitted Preservatives |
SOURCE
JECFA
JECFA ADI
JECFA ADI Values
JECFA ADI records and evaluation years.
| Jurisdiction | Chemical name | JECFA no. | CAS | ADI | ADI upper | Function | Evaluation year |
|---|---|---|---|---|---|---|---|
| JECFA | Mixed TOCOPHEROLS concentrate | - | 59-02-9 (Vitamin E) | 0-2 mg/kg bw | 2 | ANTIOXIDANT | 1973 |
| JECFA | TOCOPHEROLS | - | - | no_data | - | - | - |
SOURCE
ingredients
ghs classifications
Cross-Reference to Cosmetics / Chemicals / Pharma
Same-CAS public rows from adjacent Roots verticals where available.
SOURCE
Cross-vertical comparison
ingredients | ghs classifications
Cross-Vertical Regulatory Divergence
This substance has different regulatory treatment across food, cosmetics, and industrial use.
SOURCE
FAQPage JSON-LD
public food renderer rows
Frequently Asked Questions
Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.
What is Tocopherols used for in food?
Tocopherols appears in food-use rows as: Antioxidant; Preservative.
Is Tocopherols / E306 safe?
This page does not assign a standalone safety verdict; it renders public regulatory evidence. ADI/reference value: ADI 0.15 mg/kg bw. EU status evidence: PUBLISHED. US/FDA evidence: GRAS.
What is the ADI for Tocopherols?
Tocopherols has this ADI/reference value in the food-safety tables: ADI 0.15 mg/kg bw. Source: EFSA/FDA.
Is Tocopherols also used in cosmetics?
Tocopherols has a same-CAS cosmetics cross-reference: Tocopherol (Vitamin E), EU status restricted.