Food Safety Substance

E216E216

E216 (E216) is a food additive with Banned in EU in the EU, GRAS in the US, and data from 6 regulatory sources.

CAS 94-13-3 E216 Indexable evidence set

FDA

GRAS

ADI / TDI

ADI 10 mg/kg bw

Codex

0 row(s)

SOURCE D1 identity resolution e number aliases | Food Additives | dsstox identifiers | 6 matched regulatory source group(s)

Substance Identity

Resolved identifiers used to render this food-safety record.

Substance name

E216

CAS

94-13-3

E-number

E216

PubChem CID

7175

Evidence tier

Indexable evidence set (13)

SOURCE EU Commission EU Food Contact Materials

EU FCM Substances

EU food-contact material rows and migration-limit fields.

Jurisdiction	FCM no.	Ref no.	Substance	Use	SML	Regulation
European Union	173	60240	4-hydroxybenzoic acid, propyl ester	additive/PPA	-	Regulation (EU) No 10/2011, Annex I

SOURCE JECFA JECFA ADI

JECFA ADI Values

JECFA ADI records and evaluation years.

Jurisdiction	Chemical name	JECFA no.	CAS	ADI	ADI upper	Function	Evaluation year
JECFA	PROPYL p-HYDROXYBENZOATE	-	94-13-3	WITHDRAWN (2006)	-	PRESERVATIVE	2006

SOURCE ingredients ghs classifications

Cross-Reference to Cosmetics / Chemicals / Pharma

Same-CAS public rows from adjacent Roots verticals where available.

SOURCE Cross-vertical comparison ingredients | ghs classifications

Cross-Vertical Regulatory Divergence

This substance has different regulatory treatment across food, cosmetics, and industrial use.

CosmeticsPropylparabenEU status: restricted Industrial / GHSDangerNITE-CMC

SOURCE FAQPage JSON-LD public food renderer rows

Frequently Asked Questions

Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.

What is E216 used for in food?

E216 appears in food-use rows as: Preservative.

Is E216 / E216 safe?

This page does not assign a standalone safety verdict; it renders public regulatory evidence. ADI/reference value: ADI 10 mg/kg bw. EU status evidence: Banned in EU. US/FDA evidence: GRAS.

What is the ADI for E216?

E216 has this ADI/reference value in the food-safety tables: ADI 10 mg/kg bw. Source: EFSA.

Is E216 also used in cosmetics?

E216 has a same-CAS cosmetics cross-reference: Propylparaben, EU status restricted.