Food Safety Substance

o-Cresol

o-Cresol is a food additive with no EU additive status row found in the EU, FDA EAFUS in the US, and data from 7 regulatory sources.

CAS 95-48-7 Indexable evidence set

FDA

FDA EAFUS

ADI / TDI

ADI No safety concern at current levels of intake when used as a flavouring agent mg/kg bw

Codex

0 row(s)

SOURCE D1 identity resolution e number aliases | Food Additives | dsstox identifiers | 7 matched regulatory source group(s)

Substance Identity

Resolved identifiers used to render this food-safety record.

Substance name

o-Cresol

CAS

95-48-7

DTXSID

DTXSID8021808

PubChem CID

335

Evidence tier

Indexable evidence set (11)

SOURCE EU Commission EU Food Contact Materials

EU FCM Substances

EU food-contact material rows and migration-limit fields.

Jurisdiction	FCM no.	Ref no.	Substance	Use	SML	Regulation
European Union	174	14740	o-cresol	monomer/macromolecule	-	Regulation (EU) No 10/2011, Annex I

SOURCE JECFA JECFA ADI

JECFA ADI Values

JECFA ADI records and evaluation years.

Jurisdiction	Chemical name	JECFA no.	CAS	ADI	ADI upper	Function	Evaluation year
JECFA	o-CRESOL	691	-	No safety concern at current levels of intake when used as a flavouring agent	-	FLAVOURING_AGENT	2000
JECFA	ACETYL o-CRESOL	-	-	no_data	-	-	2000
JECFA	o-CRESOL ACETATE	-	-	no_data	-	-	2000
JECFA	alpha-ETHOXY-o-CRESOL	-	-	no_data	-	-	2000
JECFA	ISOPROPYL-o-CRESOL	-	-	no_data	-	-	2000

SOURCE ATSDR ATSDR MRL

ATSDR MRL Data

ATSDR minimal-risk-level rows by route and duration.

Jurisdiction	Chemical	Route	Duration	MRL	Critical effect	Status	Year
United States	4,6-DINITRO-O-CRESOL	Oral	Acute	0.004 mg/kg/day	Neurol	Final	2018
United States	4,6-DINITRO-O-CRESOL	Oral	Intermediate	0.004 mg/kg/day	Neurol	Final	2018

SOURCE ingredients ghs classifications

Cross-Reference to Cosmetics / Chemicals / Pharma

Same-CAS public rows from adjacent Roots verticals where available.

SOURCE Cross-vertical comparison ingredients | ghs classifications

Cross-Vertical Regulatory Divergence

This substance has different regulatory treatment across food, cosmetics, and industrial use.

CosmeticsO-CresolEU status: restricted Industrial / GHSDangerNITE-CMC

SOURCE FAQPage JSON-LD public food renderer rows

Frequently Asked Questions

Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.

What is o-Cresol used for in food?

o-Cresol appears in food-use rows as: FLAVORING AGENT OR ADJUVANT.

Is o-Cresol safe?

This page does not assign a standalone safety verdict; it renders public regulatory evidence. ADI/reference value: ADI No safety concern at current levels of intake when used as a flavouring agent mg/kg bw. US/FDA evidence: FDA EAFUS.

What is the ADI for o-Cresol?

o-Cresol has this ADI/reference value in the food-safety tables: ADI No safety concern at current levels of intake when used as a flavouring agent mg/kg bw. Source: WHO JECFA.

Is o-Cresol also used in cosmetics?

o-Cresol has a same-CAS cosmetics cross-reference: O-Cresol, EU status restricted.