Food Safety Substance
Collagen
Collagen is a food additive with Not novel food in the EU, FDA has no questions in the US, and data from 4 regulatory sources.
Substance Identity
Resolved identifiers used to render this food-safety record.
Multi-Jurisdiction Comparison
Side-by-side status rows for the same resolved substance across public food regulators.
| Jurisdiction | Authority | Status | Evidence |
|---|---|---|---|
| European Union | EU Commission | Not novel food | - |
| United States | FDA | FDA has no questions | GRAS notice |
FDA GRAS Status
US FDA GRAS notice evidence from enriched and notice tables.
| Jurisdiction | GRN | Substance | FDA response | Intended use | Basis | Notifier |
|---|---|---|---|---|---|---|
| United States | 21 | Pork collagen | FDA has no questions | Use in meat products as a binder and purge reducing agent at levels of 1.0 to 3.5 percent | Scientific procedures | AMPC, Inc. |
| United States | 1046 | Collagenase enzyme preparation from genetically modified Streptomyces violaceoruber expressing a collagenase gene | FDA has no questions | Intended for use as an enzyme in processing beef jerky, marinated and injected meat, and sausage casings, at a level up to 10.9 mg Total Organic Solids (TOS)/kg. | Scientific procedures | Nagase & Co. Ltd. |
| United States | 1171 | Collagen polypeptide produced by Escherichia coli K-12 S9188 | FDA has no questions | Intended for use as a source of collagen polypeptides in various foods at the maximum use levels specified in Table 1 of the response letter. | Scientific procedures | Geltor, Inc. |
| United States | 21 | Pork collagen | FDA has no questions | Use in meat products as a binder and purge reducing agent at levels of 1.0 to 3.5 percent | Scientific procedures | AMPC, Inc. |
| United States | 1046 | Collagenase enzyme preparation from genetically modified <i>Streptomyces violaceoruber</i> expressing a collagenase gene | FDA has no questions (in PDF) | Intended for use as an enzyme in processing beef jerky, marinated and injected meat, and sausage casings, at a level up to 10.9 mg Total Organic Solids (TOS)/kg. | Scientific procedures | Nagase & Co. Ltd. |
| United States | 1171 | Collagen polypeptide produced by <i>Escherichia coli<i/> K-12 S9188 | FDA has no questions (in PDF) | Intended for use as a source of collagen polypeptides in various foods at the maximum use levels specified in Table 1 of the response letter. | Scientific procedures | Geltor, Inc. |
JECFA ADI Values
JECFA ADI records and evaluation years.
| Jurisdiction | Chemical name | JECFA no. | CAS | ADI | ADI upper | Function | Evaluation year |
|---|---|---|---|---|---|---|---|
| JECFA | COLLAGENASE from STREPTOMYCES VIOLACEORUBER expressed in S. VIOLACEORUBER | - | - | NOT SPECIFIED | - | ENZYME_PREPARATION | 2021 |
Cross-Reference to Cosmetics / Chemicals / Pharma
Same-CAS public rows from adjacent Roots verticals where available.
Cross-Vertical Regulatory Divergence
This substance has different regulatory treatment across food, cosmetics, and industrial use.
Frequently Asked Questions
Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.
What is Collagen used for in food?
Collagen appears in food-use rows as: protein.
Is Collagen safe?
This page does not assign a standalone safety verdict; it renders public regulatory evidence. ADI/reference value: JECFA ADI NOT SPECIFIED. EU status evidence: Not novel food. US/FDA evidence: FDA has no questions.
What is the ADI for Collagen?
Collagen has this ADI/reference value in the food-safety tables: JECFA ADI NOT SPECIFIED. Source: JECFA 2021.
Is Collagen also used in cosmetics?
Collagen has a same-CAS cosmetics cross-reference: Collagen Extract, EU status permitted.