Food Safety Substance
Sodium pyrophosphateE450I
Sodium pyrophosphate (E450I) is a food additive with Approved in the EU, GRAS in the US, and data from 7 regulatory sources.
CAS 7758-16-9
E450I
Indexable evidence set
FDA
GRAS
ADI / TDI
ADI 40 mg/kg bw
Codex
0 row(s)
SOURCE
D1 identity resolution
e number aliases | Food Additives | dsstox identifiers | 7 matched regulatory source group(s)
Substance Identity
Resolved identifiers used to render this food-safety record.
Substance name
Sodium pyrophosphate
CAS
7758-16-9
E-number
E450I
DTXSID
DTXSID7044261
PubChem CID
24451
Evidence tier
Indexable evidence set (14)
SOURCE
EU Commission
FDA | Health Canada | Codex Alimentarius
Multi-Jurisdiction Comparison
Side-by-side status rows for the same resolved substance across public food regulators.
| Jurisdiction | Authority | Status | Evidence |
|---|---|---|---|
| European Union | EU Commission | Approved | - |
| Canada | Health Canada | Listed | Stabilizing agent |
SOURCE
Health Canada
Health Canada Status
Health Canada food-additive permissions by functional class and food scope.
| Jurisdiction | Class | Permitted foods | Maximum level | List |
|---|---|---|---|---|
| Canada | Stabilizing agent | (a)Blend of prepared fish and prepared meat as set out in paragraph 18.1.3(g) of Volume 18 of the Food Compositional Standards Document | (a)If used singly, the amount not to exceed 1,500 ppm, calculated as sodium phosphate, dibasic. If used in any combination with other phosphate salts, the total combined amount not to exceed 4,000 ppm, calculated as sodium phosphate, dibasic, provided that the amount of sodium pyrophosphate, tetrabasic does not exceed 1 500 ppm, calculated as sodium phosphate, dibasic. | List of Permitted Emulsifying, Gelling, Stabilizing or Thickening Agents |
| Canada | Emulsifying, stabilizing or thickening agent | (b)Cream cheese spread; Cream cheese spread with (naming the added ingredients); Processed (naming the variety) cheese; Processed cheese food; Processed cheese food with (naming the added ingredients); Processed cheese... | (b)If used singly, the amount not to exceed 3.5%. If used in any combination with other phosphate salts, citrate salts, tartrate salts or sodium gluconate, the total combined amount not to exceed 4.0%, calculated as anhydrous salts, provided that the total amount of phosphate salts does not exceed 3.5%, calculated as anhydrous salts. | List of Permitted Emulsifying, Gelling, Stabilizing or Thickening Agents |
| Canada | Emulsifying, stabilizing or thickening agent | (c)Unstandardized foods | (c)Good Manufacturing Practice | List of Permitted Emulsifying, Gelling, Stabilizing or Thickening Agents |
| Canada | Stabilizing agent | Blend of prepared fish and prepared meat as set out in paragraph 18.1.3(g) of Volume 18 of the Food Compositional Standards Document | If used singly, the amount not to exceed 1,500 ppm, calculated as sodium phosphate, dibasic. If used in any combination with other phosphate salts, the total combined amount not to exceed 4,000 ppm, calculated as sodium phosphate, dibasic, provided that the amount of sodium pyrophosphate, tribasic does not exceed 1 500 ppm, calculated as sodium phosphate, dibasic. | List of Permitted Emulsifying, Gelling, Stabilizing or Thickening Agents |
| Canada | To reduce processing losses and to reduce thaw drip | - | Total amount of added phosphate not to exceed 5,000 ppm, calculated as sodium phosphate, dibasic. | List of Permitted Food Additives with Other Purposes of Use |
| Canada | To reduce processing losses and to reduce thaw drip | - | Total amount of added phosphate not to exceed 5,000 ppm, calculated as sodium phosphate, dibasic. | List of Permitted Food Additives with Other Purposes of Use |
| Canada | Acidity regulator | Unstandardized foods | Good Manufacturing Practice | List of Permitted Acidity Regulators and Acid-Reacting Materials |
| Canada | Sequestering agent | (a) Canned crustaceans; Canned fish; Canned molluscs; Other canned marine invertebrates | (a) Total amount of added phosphate not to exceed 5,000 ppm, calculated as sodium phosphate, dibasic. | List of Permitted Sequestering Agents |
| Canada | Sequestering agent | (a) Canned crustaceans; Canned fish; Canned molluscs; Other canned marine invertebrates | (a) Total amount of added phosphate not to exceed 5,000 ppm, calculated as sodium phosphate, dibasic. | List of Permitted Sequestering Agents |
SOURCE
EU Commission
EU Food Contact Materials
EU FCM Substances
EU food-contact material rows and migration-limit fields.
| Jurisdiction | FCM no. | Ref no. | Substance | Use | SML | Regulation |
|---|---|---|---|---|---|---|
| European Union | - | - | disodium pyrophosphate | - | - | Regulation (EC) No 450/2009, Register v1.1 |
SOURCE
JECFA
JECFA ADI
JECFA ADI Values
JECFA ADI records and evaluation years.
| Jurisdiction | Chemical name | JECFA no. | CAS | ADI | ADI upper | Function | Evaluation year |
|---|---|---|---|---|---|---|---|
| JECFA | ACID SODIUM PYROPHOSPHATE | - | - | no_data | - | - | 1982 |
| JECFA | ACID TRISODIUM PYROPHOSPHATE | - | - | no_data | - | - | 2001 |
| JECFA | SODIUM PYROPHOSPHATE | - | - | no_data | - | - | 1982 |
| JECFA | DISODIUM PYROPHOSPHATE | - | 7758-16-9 | no_data | - | ACIDITY_REGULATOR, RAISING_AGENT, SEQUESTRANT | 1982 |
| JECFA | TETRASODIUM PYROPHOSPHATE | - | 7722-88-5 | no_data | - | ACIDITY_REGULATOR, EMULSIFIER, SEQUESTRANT | 1982 |
SOURCE
ingredients
ghs classifications
Cross-Reference to Cosmetics / Chemicals / Pharma
Same-CAS public rows from adjacent Roots verticals where available.
SOURCE
Cross-vertical comparison
ingredients | ghs classifications
Cross-Vertical Regulatory Divergence
This substance has different regulatory treatment across food, cosmetics, and industrial use.
SOURCE
FAQPage JSON-LD
public food renderer rows
Frequently Asked Questions
Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.
What is Sodium pyrophosphate used for in food?
Sodium pyrophosphate appears in food-use rows as: emulsifier|stabilizer; Stabilizing agent.
Is Sodium pyrophosphate / E450I safe?
This page does not assign a standalone safety verdict; it renders public regulatory evidence. ADI/reference value: ADI 40 mg/kg bw. EU status evidence: Approved. US/FDA evidence: GRAS.
What is the ADI for Sodium pyrophosphate?
Sodium pyrophosphate has this ADI/reference value in the food-safety tables: ADI 40 mg/kg bw. Source: food_additives.
Is Sodium pyrophosphate also used in cosmetics?
Sodium pyrophosphate has a same-CAS cosmetics cross-reference: Disodium Pyrophosphate, EU status permitted.