Food Safety Substance

Indole

Indole is a food additive with no EU additive status row found in the EU, FDA EAFUS in the US, and data from 6 regulatory sources.

CAS 120-72-9 Indexable evidence set

FDA

FDA EAFUS

ADI / TDI

ADI No safety concern at current levels of intake when used as a flavouring agent

Codex

0 row(s)

SOURCE D1 identity resolution e number aliases | Food Additives | dsstox identifiers | 6 matched regulatory source group(s)

Substance Identity

Resolved identifiers used to render this food-safety record.

Substance name

Indole

CAS

120-72-9

DTXSID

DTXSID0020737

PubChem CID

798

Evidence tier

Indexable evidence set (11)

SOURCE EU Commission EU Food Contact Materials

EU FCM Substances

EU food-contact material rows and migration-limit fields.

Jurisdiction	FCM no.	Ref no.	Substance	Use	SML	Regulation
European Union	383	72160	2-phenylindole	additive/PPA	15 mg/kg	Regulation (EU) No 10/2011, Annex I
European Union	692	52320	2-(4-dodecylphenyl)indole	additive/PPA	0,06 mg/kg	Regulation (EU) No 10/2011, Annex I

SOURCE JECFA JECFA ADI

JECFA ADI Values

JECFA ADI records and evaluation years.

Jurisdiction	Chemical name	JECFA no.	CAS	ADI	ADI upper	Function	Evaluation year
JECFA	INDOLE	1301	-	No safety concern at current levels of intake when used as a flavouring agent	-	FLAVOURING_AGENT	2004
JECFA	3-METHYLINDOLE	-	-	no_data	-	-	2004

SOURCE ingredients ghs classifications

Cross-Reference to Cosmetics / Chemicals / Pharma

Same-CAS public rows from adjacent Roots verticals where available.

SOURCE Cross-vertical comparison ingredients | ghs classifications

Cross-Vertical Regulatory Divergence

This substance has different regulatory treatment across food, cosmetics, and industrial use.

CosmeticsIndoleEU status: permitted Industrial / GHSDangerNITE-CMC

SOURCE FAQPage JSON-LD public food renderer rows

Frequently Asked Questions

Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.

What is Indole used for in food?

Indole appears in food-use rows as: FLAVORING AGENT OR ADJUVANT.

Is Indole safe?

This page does not assign a standalone safety verdict; it renders public regulatory evidence. ADI/reference value: ADI No safety concern at current levels of intake when used as a flavouring agent . US/FDA evidence: FDA EAFUS.

What is the ADI for Indole?

Indole has this ADI/reference value in the food-safety tables: ADI No safety concern at current levels of intake when used as a flavouring agent . Source: food_substances.

Is Indole also used in cosmetics?

Indole has a same-CAS cosmetics cross-reference: Indole, EU status permitted.